Yang Xia
Professor
The University of Texas Health Science Center
United States
Biography
Dr. Yang Xia is currently working as a Professor in the Department of Biochemistry & Molecular Biology at the University of Texas-Health Science Centre. She had completed her doctoral degree in Molecular Pathology Program from the Graduate School of Biomedical Science, The University of Texas-Health Science Centre. She is a member of Society of Chinese Bio scientists in America (Houston Chapter), American Heart Association, Council on High Blood Pressure Research, Council on Basic Cardiovascular Research. She holds editorial positions in various journals.
Research Interest
My laboratory focuses on translational research of cardiovascular diseases including hypertension, preeclampsia, priapism, chronic kidney disease and blood disorders (sickle cell disease). Our goal is to translate our discovery-driven basic science smoothly and quickly to clinics to benefit human health. To accomplish this goal, we have conducted multiple non-biased screening (including metabolomic screening and gene array) to identify potential pathogenic markers for the diseases. Extending from our initial screen, we have conducted preclinical studies using both pharmacological and genetic approaches to determine the pathophysiological role of these newly identified molecules in the disease in animal models. Finally, we have conducted human translational research to determine whether these newly identified pathogenic markers are diagnostic makers for early detection and therapeutic targets for the diseases. Overall, we use three platforms including non-biased screen, preclinical animal studies and human translational studies to perform translational research in multiple cardiovascular diseases