Recommended Global Biochemistry Conferences
Metabolomics Meeting 2019
Conference Series LLC Ltd invites you for 14th International Conference on Metabolomics and Enzymology during March 18-19, 2019 New York, USA. This is a fabulous open door for the representatives from Universities and Institutes to communicate with the world-class Scientists.
Theme: Focuses on the development of Metabolomics
Metabolomics Meeting 2019 conference will be an investigation of New Research Innovations in Metabolomics and a spread of the most recent advancements and methodologies in Metabolomics displaying, Proteomics, Systems Biology, Genomics, Precision Medicine, Lipidomics, LC-MS and GC-MS Techniques, Bioinformatics, Plant Metabolomics, Clinical metabolomics, computational science, metabolomic disorders, Nutritional Metabolomics, Therapeutic Metabolomics and more. Metabolomics is of enthusiasm to clinicians in light of the fact that it might prompt enhancements in the conclusion and medications of human illnesses. Metabolomics makes utilization of systematic procedures, for example, spectroscopy, chromatography, and multivariable investigation. Metabolomics permits researchers to improve knowledge and to help devise effective methods of health research.
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Target Audience will be personnel from both industrial and academic fields which include; CEOs, COOs, Directors, Vice Presidents, Co-directors, Biochemists, Biotechnologists, Managing Directors, Industry Safety Officers, Environmental & Plant Scientists, Doctorates, Professors, Post Doctorate Fellows, Vendors of Consumer Products/ Managers, Pharmaceutical Scientists, Students from the related fields.
Session & Tracks
Track 1: Cancer Therapeutic Approaches
Cancer cells are known to possess a highly unique metabolic phenotype. Hence development of specific biomarkers in oncology is necessary and they are used to detect the presence of cancer, determine prognosis, and/or assess the viability of treatment. Recent innovations have empowered the examination of numerous potential biomarkers and recharged enthusiasm for growing new biomarkers. Metabolomics allows for a global assessment of a cellular state within the context of the immediate environment, considering genetic regulation, altered kinetic activity of enzymes, and changes in metabolic reactions. Thus, Metabolomics is growing in the field of oncology with particular attention to its application as a biomarker in cancer diagnosis, assessing treatment effects, and in the development of novel therapeutics.
1.1 Role of NMR based metabolomics in Cancer
1.2 Use of metabolomics in Cancer Biomarker discovery
1.3 Applications of metabolomics in Cancer studies
1.4 Future of metabolomics in Oncology
Track 2: Metabolomics in Precision Medicine
Precision medicine is an approach to manage finding exact solutions to fathom the natural reason of infection. Precision medicine is a rising methodology for illness treatment. Accuracy offers cutting edge answers for augment your achievement in translational examination. Pharmacometabolomics, an emerging field in metabolomics, plays a key role in precision medicine.
2.1 Role of metabolomics in Precision medicine
2.2 Novel biomarkers for Precision medicine
2.3 Novel applications of Metabolomics in drug discovery
Track 3: Therapeutic Metabolomics
Metabolomics had profound importance in recent years in context to its applications in the field of drug discovery and drug development. With recent advances in the field of metabolomics it can be proved as a major tool for innovative therapeutic discoveries. In the agricultural/chemical industry, metabolomics may be used to develop herbicides and pesticides. With increasing importance being placed on health and safety related aspects of our food, metabolomics can potentially be a valuable tool in food processing and quality control, or in plant breeding for improved crop varieties and in the development of novel food stuffs. Centre for Metabolomics is associated with therapeutic metabolomics. Computational immunology is a field of science that incorporates high-throughput genomic and bioinformatics ways to deal with immunology.
3.1 Drug target discovery
3.2 Strategies in biomarker discovery
3.3 Metabolomics – an innovative tool for novel therapeutics.
Track 4: Metabolic Profiling
Metabolic profiling is an assessment of low-molecular-weight metabolites and their intermediates in unicellular to multicellular biological systems that reflects the dynamic response to genetic modification. The measurement and evaluation of the endogenous metabolite profile from a biological sample have provided many opportunities to investigate the changes induced by external stimuli. Metabolomic profiling has been used to recognize novel biomarkers and instruments of cardiovascular hazard. Metabolomic approach gives novel encounters into the robotic investigations of tumour diagnosis. Metabolic profiling can supplement routine frameworks and other "omics" propels in inquiring about preclinical prescription change issues.
4.1 Biomolecule profiling for the diagnosis of inborn errors of metabolism
4.2 Targeted metabolite profiling
4.3 High throughput metabolite profiling
4.4 NMR based drug metabolite profiling
4.5 Current challenges in metabolite profiling technologies
Track 5: Transcriptomics
The biological processes between different levels of “omics” are highly complex, a combined analysis of metaboliteand gene expression data will help discover and evaluate the underlying pathway mechanisms and identify genes that influence the metabolome. Transcriptomic studies measure the simultaneous expression of up to thousands of genes and can be used to identify which genes are up- or down-regulated under certain conditions. Metabolomic studies provide information on the metabolites found within a biological sample. These two branches seek to uncover the underlying systems biology and when combined they can be successful in predicting gene functions or identifying gene-metabolite associations.
5.1 Integration of transcriptomics & metabolomics
5.2 Potential of metabolomics as a functional genomics tool.
Track 6: Lipidomics
The pivotal role of lipids in cell, tissue and organ physiology is demonstrated by a large number of genetic studies and by many human diseases that involve the disruption of lipid metabolic enzymes and pathways. Examples of such diseases include cancer, diabetes, as well as neurodegenerative and infectious diseases. So far, the outbreak of information in the fields of genomics and proteomics has not been matched by a corresponding advancement of knowledge in the field of lipids, which is largely due to the complexity of lipids and the lack of powerful tools for their analysis. Novel analytical approaches mainly LC and MS for system-level analysis of lipids and their interacting partners now make this field a promising area of biomedical research, with a variety of applications in drug and biomarker development. Mass spectrometry, largely due to its analytical power and rapid development of new instruments and techniques, has been widely used in lipidomics.
6.1 Analytical techniques in Lipidomics
6.2 Lipidomics & risk of Cardiovascular diseases and diabetes
6.3 Lipid profiling and its potential applications
6.4 Statistical analysis of Lipidomics.
Track 7: Metabolic Modelling
Metabolic modelling allows a deep insight into the molecular mechanisms of a particular organism. A reconstruction process breaks down metabolic pathways into their respective reactions and enzymes, and analyses them within the perspective of the entire network. It collects all the relevant metabolic information of an organism and compiles it in a mathematical model. A deep analysis of these reconstructed pathways can allow identification of key features of metabolism such as growth yield, resource distribution, network robustness, and gene essentiality. This information can then be applied to create novel biotechnological methods.
7.1 Molecular modelling methods in metabolomics
7.2 Computational approaches for metabolic modelling
7.3 Qualitative modelling of metabolic networks.
Track 8: Clinical Metabolomics
Conventional biological diagnostic procedures are based on a time-consuming series of sequential biochemical tests. The rise of “omic” technologies offers the complete picture of basic molecules that build a biological system at different levels. Metabolomics is the most recent “omic” technology based on biochemical characterization of metabolites and their changes pertaining to genetic and environmental factors. Metabolomics, when used as a translational research tool, can offer a link between the laboratory and clinic, and produce results in a lesser time.
8.1 Challenges & developments in clinical metabolomics
8.2 Clinical applications of metabolomics in diabetes treatment
8.3 Clinical risk prediction using metabolomics
Track 9: Plant Metabolomics
Metabolomics is the examination of endogenous and exogenous low atomic mass metabolites inside of a cell, tissue, or biofluid of a life form in light of an outer stressor. Plant Metabolomics is to contemplate the plant framework at the sub-atomic level giving complete characterization of metabolome of plants under particular conditions. Using Metabolomics, a better understanding of the correlation between genes and the biochemical composition of a plant tissue in response to its environment can be obtained, and this information can be further used to assess gene function.
9.1 Plant metabolic network
9.2 Application of LC-MS in plant metabolomics
Track 10: Nutritional Metabolomics
Metabolomics has been emerged as a significant tool in many disciplines. In food science, metabolomics has recently risen as a tool for quality, processing and safety of raw materials and final products. Nutrigenomics provides a gateway to study the effect of foods and food constituents on gene expression. Applications of nutrigenomics include the genomic, transcriptomic, proteomic, and metabolomic studyof foods for compound profiling, authenticity related to food safety; the development of new transgenic foods, food contaminants, and whole toxicity studies; new investigations on food bioactivity, food effects on human health.
10.1 Emerging role of metabolomics in human nutrition
10.2 Metabolomics in Plant nutrition – Emerging methodologies
10.3 Food metabolome and its signature in Human samples
10.4 Recent advances in nutritional metabolomics
10.5 Future of nutritional metabolomics & research needs
Track 11: Metabolomic databases
Metabolomics relies on a variety of bioinformatic tools aiming to derive information from data. Data acquisition with chromatography-coupled mass spectrometry yields high volumes of raw data that need to be processed to achieve proper biochemical data that eventually can be presented for statistics and pathway analysis in a coherent manner. A variety of new tools and algorithms have recently been developed that help in this process. If cutting-edge methods are used, we can confidently interpret signals that can neither be identified by reference standards and are used for novel researches.
11.1 Human metabolome database
11.2 Databases and software for metabolomic studies
Track 12: Analytical Metabolomics
To obtain holistic metabolic profiles from complex samples, such as biological fluids or tissue extracts, we require a powerful, high resolution and information rich analytical methods and for this, spectroscopic technologies are generally used. Mass spectrometry, coupled to liquid chromatography (LC–MS), is increasingly being used for such investigations as a result of the significant advances in both technologies over the past decade.
12.1 Modern analytical techniques in metabolomic analysis
12.2 Applications of NMR based metabolomics
12.3 Recent advances in NMR based metabolomics
Track 13: Xenobiotics
Xenobiotics are encountered by humans on a daily basis and include drugs, environmental pollutants, cosmetics, and even components of the diet. These chemicals undergo metabolism and detoxication to produce numerous metabolites, some of which have the potential to cause adverse effects such as toxicity. They can also block the action of enzymes or receptors used for endogenous metabolism or affect the efficacy of a co-administered drug. Therefore, it is essential to determine the full metabolic effects that these chemicals have on the body. Metabolomics, the comprehensive analysis of small molecules in a biofluid, can reveal biologically relevant perturbations that result from xenobiotic exposure.
13.1 Challenges and Opportunities of xenobiotics in metabolomics
13.2 Profiling the reactive metabolites of xenobiotics using metabolomic technologies.
13.3 Metabolomics as a global biochemical approach to drug response and disease
Track 14: Metabolomics & Biotechnology
By studying the complete set of metabolites within a microorganism and monitoring its interactions between its development processes and the environment, metabolomics can potentially provide a more accurate picture of the actual physiological state of the cell. Microbial metabolomics has received much attention in recent years mainly because it supports and complements a wide range of microbial research areas from new drug discovery efforts to metabolic engineering.
14.1 Microbial metabolomics with higher throughput
14.2 Custom made separation for microbial metabolomics
14.3 Application of microbial metabolomics
Track 15: Metabolomics & Pharmacology
Pharmacogenomics has some impact in clinical practice, through its use to select patient subgroups who will enjoy efficacy without side effects when treated with certain drugs. However, pharmacogenomics, has had less impact than initially predicted. One reason for this is that many diseases, and the way in which the patients respond to drug treatments, have both genetic and environmental elements. Pure genomics is almost blind to the environmental elements. A new methodology has emerged, termed pharmacometabolomics that is concerned with the prediction of drug effects through the analysis of pre-dose, biofluid metabolite profiles, which reflect both genetic and environmental influences on human physiology.
15.1 Implications of Clinical Pharmacology
15.2 Pharmaceutical research & Metabolomics in the New born
Track 16: Metabolic syndrome
Metabolic syndrome is a cluster of physiological, biochemical, clinical, and metabolic factors that directly accelerates the risk of cardiovascular disease and diabetes mellitus. Insulin resistance, visceral adiposity, atherogenic dyslipidemia, endothelial dysfunction, genetic susceptibility, elevated blood pressure, hypercoagulable state, and chronic stress are the several factors which constitute the syndrome. Lifestyle modification remains the initial intervention of choice for such disorders. Modern lifestyle modification therapy combines specific recommendations on diet and exercise with behavioural strategies. The pharmacological and metabolomic datahelps in overcoming such problems.
16.1 Dietary patterns in Metabolic syndrome
16.2 Impact of metabolic syndrome on cardiovascular disease
16.3 Genomics of paediatric metabolic syndrome
The Future of Metabolomics' gives complete understanding into the compelling utilization of metabolomics all through drug discovery, preclinical development and clinical trials. The report also highlights the use of metabolomics in maximizing and sustaining revenues post-marketing and in the development of clinical diagnostics.
Scope & Importance:
The emerging techniques of metabolomics make it an ideal tool for new innovations in the pharmaceutical, preventive healthcare, and agricultural industries. Discovery of Biomarkers and drug safety screens are two examples where metabolomics has already proven its mark. In the future, with the accessibility of personalised metabolomics, we will potentially be able to track the trends of our own metabolome for personalised precision drugs and improved treatment strategies. Personalised precision treatment is likely to be more effective than our current medical approaches.
Metabolomics is now being extensively used in pharmaceutical and biotechnology industries for biomarker and drug discovery; pharmaceutical and biotechnology industries are expected to grow at a high rate in coming years, which is expected to boost the growth of the market.
The National Institutes of Health(NIH) grants funds to Metabolomics program. This aims to elevate national capacity in metabolomics by supporting the development of next generation technologies to enhance the sensitivity and speed with which specific elements of the cellular metabolome can be identified and quantified, providing opportunities, rising the inventions of chemically identifiable metabolites through the synthesis and availability of high quality reference standards, and by promoting data sharing and collaboration.
Rise in the number of clinical trials, toxicological studies, and health awareness for nutritional products, rapid growth of metabolomics data analysis software and solutions, and use of metabolomics as diagnostic tool for biomarker, screening of diseases is expected to propel the growth of this market.
Why to attend?
Meet your target market with recent business reports on Metabolomics which manifests the tremendous growth in market value for metabolomics technology till 2019. Since metabolomics interrelated with omics sciences like Genomics, precision Medicine, Proteomics, Lipidomics and Transcriptomics, it would be a great opportunity for companies dealing with Analytical instruments useful in these fields. Also, many upcoming students and researchers can benefit themselves by participating world class International workshops, symposia during the conference which will be conducted by experts in their respective fields.
Why New York?
The U.S. is the prime market for metabolomics due to the rising acceptance of personalized medicines and growing focus of stakeholders on research projects involving metabolites, amino acid composition, and associated biomolecules in the country. In 2017, North America commanded the largest share of the metabolomics market, followed by Europe.
Major Industries in the global metabolomics market are Agilent Technologies, Inc. (U.S.), Bruker Corporation (U.S.), Danaher Corporation (U.S.), Thermo Fisher Scientific, Inc. (U.S.), Shimadzu Corporation (Japan), Waters Corporation (U.S.) Bio-Rad Laboratories (U.S.), Biocrates Life Sciences AG
- Metabolomics Instrumentation Technology Product Manufacturers
- Researchers and Scientists
- Metabolomics Industry Consulting Firms
- Metabolomics Research and Development (R&D) Companies
- Healthcare Institutions
- Research Institutes
- Market Research and Consulting Firms
- Directors/Managers & Business Delegates,
- Director of Laboratories, Universities,
- Post-Doctoral Fellows,
- Biomedical Research companies
Glance at Market of Metabolomics:
The market is mainly driven by the increasing research funding for metabolomics from governments and private investors, growing demand for personalized medicine in the U.S. and Europe, and the increasing need for toxicology testing. However, low adoption rates and data complexity inhibits the growth of the metabolomics market to a certain extent. Metabolomics science is used extensively in biomarker discovery and drug assessment. Thus, the rapid growth experienced by pharmaceutical and biotechnology industries is assisting the growth of the metabolomics market.
In 2017, North America was the market leader with a share of ~42% of the global market, followed by Europe with a share of ~38%. The presence of large number of analytical equipment manufacturers has contributed significantly to the North American and European metabolomics market. The growth in this market is driven by the growing pharmaceutical and biotechnology industries.
The global metabolomics market was valued at $565 million in 2014, and $1030 million in 2016. and is expected to grow at a CAGR of 14.6% during the forecast period (2016–2021) to reach $2410 million by 2022.
Statistics which shows growth in importance of Metabolomics :
Statistics of Industries Associated with Metabolomics:
North America was the market leader with a share of ~42% of the global market, followed by Europe with a share of ~38%. The presence of a large number of analytical equipment manufacturers has contributed significantly to the North American and European metabolomics market. However, the Asia-Pacific region represents a significant growth opportunity for the metabolomics market during the forecast period of 2014 to 2019. The APAC market is expected to grow at a CAGR of 23% during the forecast period. The growth in this market is driven by the growing pharmaceutical and biotechnology industries.
The major players in the metabolomics market include Thermo Fisher Scientific (U.S.), Metabolon, Inc. (U.S.), Danaher Corporation (U.S.), Shimadzu Corporation (Japan), Waters Corporation (U.S.), Agilent Technologies (U.S.), and Bruker Corporation (U.S.)
Fund Allotment towards Metabolomics Research:
The National Institutes of Health has provided tens of millions of dollars in new funding to support three new Comprehensive Metabolomics Centers at Mayo Clinic, the University of Kentucky, and the University of Florida.
These three centers will receive an estimated $9 million to $10 million each over the next five years to create resources and initiate research programs that will ramp up the national metabolomics science capabilities.
Funding to UC San Diego for this project is $6 million over five years, part of a total investment by the NIH of $51.4 for the metabolomics project. The awards are supported by the NIH Common Fund.
Mayo Clinic is one of six new federally-funded Comprehensive Metabolomics centres to support medical research on metabolomics — the study, at the cellular level, of how molecules are metabolized in the body. The award from the National Institutes of Health (NIH) is for $8.8 million over five years.
Major Metabolomics Related Associations across the Globe:
- American association for the advancement of science
- American association for clinical chemistry
- American association for cancer research
- American association of pharmaceutical scientists
- American cancer society
- Bioinformatics society of India
- Nutrigenomics Organization
- The British Society for Genetic Medicine
- The Genetics Society
- Netherlands metabolomics center
- The Australian biotechnology association
- Human Proteome Organization
- Indiana Proteomics Consortium
- Proteome Society
- European federation of biotechnology
- Australasian Proteomics Society
- Clinical Genetics Society
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