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7th International Conference and Expo on Metabolomics

Orlando, USA

Magdaleno Rodríguez Daniel Roberto

Magdaleno Rodríguez Daniel Roberto

Instituto Politecnico Nacional, Mexico

Title: Efficiency and safety of combining silybin, lipoteichoic acid and selenomethionine in the treatment of non alcoholic fatty liver

Biography

Biography: Magdaleno Rodríguez Daniel Roberto

Abstract

Obesity has become a public global health, we cannot lose sight that this disease has reached epidemic global proportions, which is why the World Health Organization (WHOby the acronym in English) calls obesity as the epidemic of the century.
The purpose of this study was to evaluate the efficacy and safety of the combination of silymarin, selenomethionine and  alphalipoecoico acid in adult patients with non alcoholic fatty liver using different dosages, comparing changes in patients receiving doses every 8 hours against the patients that received doses every 12 hours. It was evaluated the biochemical changes through blood, morphological determinations by ultrasound and anthropometric measurements.
It was a longitudinal, prospective and comparative study during 12 weeks. This study was conducted   under 88 exogenous obese patients, aged between 18 and 60 years of both sexs with Body Mass Index (BMI by the acronym in English) between 30 and 45 kg/m2 and diagnosed with fatty liver confirmed by ultrasound with sub-clinical alterations in liver enzymes. Patients were randomized into two groups of 44 subjects each and were administered for three months the combination of silymarin, selenomethionine and  alphalipoecoico acid with dosage of one capsule every 8 hours (group 1) and every 12 hours (group 2).