Kyushu University, Japan
Yukio Fujiki and his colleagues investigate cellular homeostasis involving subcellular organelles such as peroxisome. His lab tackles the problems involving membrane assembly, matrix protein import, morphogenesis and homeostasis of peroxisomes. His group successfully identified and isolated more than a dozen PEX genes including the first Zellweger gene PEX2. He and his colleagues unveil the roles of peroxins in peroxisome biogenesis and the pathogenesis of PBDs from the viewpoint of dysregulation of peroxisome homeostasis.